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On the Cover: Multiple photoreceptors modulate plant growth and development in response to the surrounding light environment. Phytochrome A, phytochrome B, and cryptochrome 1 play a key role in modulating de-etiolation and flowering time in Arabidopsis. Neff and Chory (pp 27-36) and Casal and Mazzella (pp 19-25) have used single, double, and triple mutants carrying null alleles of the apoproteins of these photoreceptors to investigate the interactions among the signals they initiate. These interactions are complex, but some common patterns have emerged. For example, there are conditions under which the action of an individual photoreceptor can occur in the absence of the other two; under other conditions mutual dependence is evident, particularly between phytochrome B and cryptochrome 1. These patterns of interaction reveal new insights into the connections among the transduction chains of the photoreceptors. (Photograph by Bettina Guarnaschelli.)