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Plant Physiol, September 2001, Vol. 127, pp. 159-172
Regulation of the Arabidopsis Transcriptome by Oxidative
Stress
Radhika
Desikan,
Soheila
A.-H.-Mackerness,1
John
T.
Hancock, and
Steven J.
Neill*
Centre for Research in Plant Science, University of the West of
England, Bristol, Coldharbour Lane, Bristol BS16 1QY, United Kingdom
(R.D., J.T.H., S.J.N.); and Department of Plant Genetics and
Biotechnology, Horticulture Research International, Wellesbourne,
Warwick CV35 9EF, United Kingdom (S.A.-H.-M.)
Oxidative stress, resulting from an imbalance in the accumulation
and removal of reactive oxygen species such as hydrogen peroxide
(H2O2), is a challenge faced by all aerobic
organisms. In plants, exposure to various abiotic and biotic stresses
results in accumulation of H2O2 and oxidative
stress. Increasing evidence indicates that H2O2
functions as a stress signal in plants, mediating adaptive responses to
various stresses. To analyze cellular responses to
H2O2, we have undertaken a large-scale analysis
of the Arabidopsis transcriptome during oxidative stress. Using cDNA
microarray technology, we identified 175 non-redundant expressed
sequence tags that are regulated by H2O2. Of
these, 113 are induced and 62 are repressed by
H2O2. A substantial proportion of these
expressed sequence tags have predicted functions in cell rescue and
defense processes. RNA-blot analyses of selected genes were used to
verify the microarray data and extend them to demonstrate that other
stresses such as wilting, UV irradiation, and elicitor challenge also
induce the expression of many of these genes, both independently of,
and, in some cases, via H2O2.
1
Present address: Department of Environment, Food
and Rural Affairs, Room 701 Cromwell House, Dean Stanley Street,
Westminster, London SW1P 3JH, UK.
*
Corresponding author; e-mail steven.neill{at}uwe.ac.uk; fax
44-117-3442904.
© 2001 American Society of Plant Physiologists
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|
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|
|
|
|
|
|
|
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|
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|
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|
|
|
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|
|
|
|
|
|
|
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|
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|
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|
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|
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|
|
|
|
|
|
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|
|
|
|
|
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140(4):
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|
|
|
|
|
|
|
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|
|
|
|
|
|
|
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140(3):
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|
|
|
|
|
|
|
I. Couee, C. Sulmon, G. Gouesbet, and A. El Amrani
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57(3):
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[Full Text]
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|
|
|
|
|
|
|
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139(4):
1773 - 1783.
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|
|
|
|
|
|
|
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139(3):
1291 - 1303.
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|
|
|
|
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|
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|
|
|
|
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[Full Text]
[PDF]
|
|
|
|
|
|
|
S. Vanderauwera, P. Zimmermann, S. Rombauts, S. Vandenabeele, C. Langebartels, W. Gruissem, D. Inze, and F. Van Breusegem
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139(2):
806 - 821.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
T. Ishikawa, Y. Morimoto, R. Madhusudhan, Y. Sawa, H. Shibata, Y. Yabuta, A. Nishizawa, and S. Shigeoka
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August 1, 2005;
46(8):
1264 - 1271.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. Wawrzynska, M. Lewandowska, M. J. Hawkesford, and A. Sirko
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J. Exp. Bot.,
June 1, 2005;
56(416):
1575 - 1590.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. Baier and K.-J. Dietz
Chloroplasts as source and target of cellular redox regulation: a discussion on chloroplast redox signals in the context of plant physiology
J. Exp. Bot.,
June 1, 2005;
56(416):
1449 - 1462.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
R. Desikan, J. T. Hancock, J. Bright, J. Harrison, I. Weir, R. Hooley, and S. J. Neill
A Role for ETR1 in Hydrogen Peroxide Signaling in Stomatal Guard Cells
Plant Physiology,
March 1, 2005;
137(3):
831 - 834.
[Full Text]
[PDF]
|
|
|
|
|
|
|
O. Radwan, S. Mouzeyar, P. Nicolas, and M. F. Bouzidi
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J. Exp. Bot.,
February 1, 2005;
56(412):
567 - 575.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. Tsukamoto, S. Morita, E. Hirano, H. Yokoi, T. Masumura, and K. Tanaka
A Novel cis-Element That Is Responsive to Oxidative Stress Regulates Three Antioxidant Defense Genes in Rice
Plant Physiology,
January 1, 2005;
137(1):
317 - 327.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. A. Schottler, H. Kirchhoff, and E. Weis
The Role of Plastocyanin in the Adjustment of the Photosynthetic Electron Transport to the Carbon Metabolism in Tobacco
Plant Physiology,
December 1, 2004;
136(4):
4265 - 4274.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. Braatsch, O. V. Moskvin, G. Klug, and M. Gomelsky
Responses of the Rhodobacter sphaeroides Transcriptome to Blue Light under Semiaerobic Conditions
J. Bacteriol.,
November 15, 2004;
186(22):
7726 - 7735.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. Mateo, P. Muhlenbock, C. Rusterucci, C. C.-C. Chang, Z. Miszalski, B. Karpinska, J. E. Parker, P. M. Mullineaux, and S. Karpinski
LESION SIMULATING DISEASE 1 Is Required for Acclimation to Conditions That Promote Excess Excitation Energy
Plant Physiology,
September 1, 2004;
136(1):
2818 - 2830.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. Lo, C. Taylor, L. Wang, L. Nowack, T.-W. Wang, and J. Thompson
Characterization of an Ultraviolet B-Induced Lipase in Arabidopsis
Plant Physiology,
June 1, 2004;
135(2):
947 - 958.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
C. Barth, W. Moeder, D. F. Klessig, and P. L. Conklin
The Timing of Senescence and Response to Pathogens Is Altered in the Ascorbate-Deficient Arabidopsis Mutant vitamin c-1
Plant Physiology,
April 1, 2004;
134(4):
1784 - 1792.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
L. Rizhsky, S. Davletova, H. Liang, and R. Mittler
The Zinc Finger Protein Zat12 Is Required for Cytosolic Ascorbate Peroxidase 1 Expression during Oxidative Stress in Arabidopsis
J. Biol. Chem.,
March 19, 2004;
279(12):
11736 - 11743.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
H. Shou, P. Bordallo, J.-B. Fan, J. M. Yeakley, M. Bibikova, J. Sheen, and K. Wang
From The Cover: Expression of an active tobacco mitogen-activated protein kinase kinase kinase enhances freezing tolerance in transgenic maize
PNAS,
March 2, 2004;
101(9):
3298 - 3303.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
V. I. Titorenko and R. A. Rachubinski
The peroxisome: orchestrating important developmental decisions from inside the cell
J. Cell Biol.,
March 1, 2004;
164(5):
641 - 645.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. Sagi, O. Davydov, S. Orazova, Z. Yesbergenova, R. Ophir, J. W. Stratmann, and R. Fluhr
Plant Respiratory Burst Oxidase Homologs Impinge on Wound Responsiveness and Development in Lycopersicon esculentum
PLANT CELL,
March 1, 2004;
16(3):
616 - 628.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
C. Bailly, J. Leymarie, A. Lehner, S. Rousseau, D. Come, and F. Corbineau
Catalase activity and expression in developing sunflower seeds as related to drying
J. Exp. Bot.,
February 1, 2004;
55(396):
475 - 483.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
R. Desikan, M.-K. Cheung, J. Bright, D. Henson, J. T. Hancock, and S. J. Neill
ABA, hydrogen peroxide and nitric oxide signalling in stomatal guard cells
J. Exp. Bot.,
January 2, 2004;
55(395):
205 - 212.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. Vandenabeele, K. Van Der Kelen, J. Dat, I. Gadjev, T. Boonefaes, S. Morsa, P. Rottiers, L. Slooten, M. Van Montagu, M. Zabeau, et al.
A comprehensive analysis of hydrogen peroxide-induced gene expression in tobacco
PNAS,
December 23, 2003;
100(26):
16113 - 16118.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
E. J. Campbell, P. M. Schenk, K. Kazan, I. A.M.A. Penninckx, J. P. Anderson, D. J. Maclean, B. P.A. Cammue, P. R. Ebert, and J. M. Manners
Pathogen-Responsive Expression of a Putative ATP-Binding Cassette Transporter Gene Conferring Resistance to the Diterpenoid Sclareol Is Regulated by Multiple Defense Signaling Pathways in Arabidopsis
Plant Physiology,
November 1, 2003;
133(3):
1272 - 1284.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
P. Casati and V. Walbot
Gene Expression Profiling in Response to Ultraviolet Radiation in Maize Genotypes with Varying Flavonoid Content
Plant Physiology,
August 1, 2003;
132(4):
1739 - 1754.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. R. Holley, R. D. Yalamanchili, D. S. Moura, C. A. Ryan, and J. W. Stratmann
Convergence of Signaling Pathways Induced by Systemin, Oligosaccharide Elicitors, and Ultraviolet-B Radiation at the Level of Mitogen-Activated Protein Kinases in Lycopersicon peruvianum Suspension-Cultured Cells
Plant Physiology,
August 1, 2003;
132(4):
1728 - 1738.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. Gilliland, D. P. Singh, J. M. Hayward, C. A. Moore, A. M. Murphy, C. J. York, J. Slator, and J. P. Carr
Genetic Modification of Alternative Respiration Has Differential Effects on Antimycin A-Induced versus Salicylic Acid-Induced Resistance to Tobacco mosaic virus
Plant Physiology,
July 1, 2003;
132(3):
1518 - 1528.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
K.-i. Hayashi, A. M. Jones, K. Ogino, A. Yamazoe, Y. Oono, M. Inoguchi, H. Kondo, and H. Nozaki
Yokonolide B, a Novel Inhibitor of Auxin Action, Blocks Degradation of AUX/IAA Factors
J. Biol. Chem.,
June 20, 2003;
278(26):
23797 - 23806.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. J. Considine, M. Goodman, K. S. Echtay, M. Laloi, J. Whelan, M. D. Brand, and L. J. Sweetlove
Superoxide Stimulates a Proton Leak in Potato Mitochondria That Is Related to the Activity of Uncoupling Protein
J. Biol. Chem.,
June 13, 2003;
278(25):
22298 - 22302.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. P. Hammond, M. J. Bennett, H. C. Bowen, M. R. Broadley, D. C. Eastwood, S. T. May, C. Rahn, R. Swarup, K. E. Woolaway, and P. J. White
Changes in Gene Expression in Arabidopsis Shoots during Phosphate Starvation and the Potential for Developing Smart Plants
Plant Physiology,
June 1, 2003;
132(2):
578 - 596.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
O. Kursteiner, I. Dupuis, and C. Kuhlemeier
The Pyruvate decarboxylase1 Gene of Arabidopsis Is Required during Anoxia But Not Other Environmental Stresses
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