This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Hall, L. M. Articles by Devine, M. D. Search for Related Content PubMed PubMed Citation Articles by Hall, L. M. Articles by Devine, M. D. Agricola Articles by Hall, L. M. Articles by Devine, M. D.

Metabolism and Enzymology

Cross-Resistance of a Chlorsulfuron-Resistant Biotype of Stellaria media to a Triazolopyrimidine Herbicide ¹

Department of Crop Science and Plant Ecology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada, S7N OWO

A biotype of Stellaria media (L.) Vill. has been identified that is highly resistant to the herbicide chlorsulfuron. Resistance is due to an altered acetolactate synthase (ALS) that is much less sensitive to chlorsulfuron than the ALS from the susceptible (S) biotype. The S biotype was extremely sensitive to D489 (N-[2,6-dichlorophenyl]-5,7-dimethyl-1,2,4-triazolo[1,5a] pyrimidine-2-sulfonamide), a member of a new class of triazolopyrimidine herbicides, while the chlorsulfuron-resistant biotype exhibited complete cross-resistance at both the whole plant and enzyme levels. ALS activity of the S biotype was reduced by approximately 90% in the presence of 0.1 micromolar D489, while that of the R biotype was reduced by less than 10%. This result suggests that the two herbicides share a common binding site on ALS. Only very slight cross-resistance at the ALS level was found to imazamethabenz, an imidazolinone herbicide.

This article has been cited by other articles:

				C. E. Whitcomb An introduction to ALS-inhibiting herbicides Toxicology and Industrial Health, February 1, 1999; 15(1-2): 232 - 240. [Abstract] [PDF]